Bringing Innovation to the Search for Biomarkers

In this Director’s Message, Dr. Gordon highlights research supported by the NIMH Small Business Innovation Research program that could advance the development of clinically relevant biomarkers.

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Likely cause of Alzheimer’s identified in new study

  • Worldwide, Alzheimer’s disease is one of the most common forms of dementia.
  • Using mouse models, researchers in Australia have identified one of the likely causes of Alzheimer’s disease. Some have dubbed the finding a “breakthrough.”
  • By studying the blood-brain barrier, the scientists have come away with a better understanding of why and how Alzheimer’s disease occurs.
  • Their findings suggest potential treatment and prevention options for the neurodegenerative condition.

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Mapping ‘Imbalance’ in Brain Anatomy Across the Lifespan

Humans are born with relatively immature brains that continue to develop in size, shape, and structure throughout childhood and adolescence. Different brain areas must develop in proportion to one another in a standardized way to achieve a mature, adult brain. Researchers at the National Institute of Mental Health (NIMH) have developed a new way to measure the degree to which the proportions of an individual person’s brain differ from the proportions typically seen in the broader population. This measurement approach, called “anatomical imbalance mapping” or AIM, yields new insights into brain development and offers tools for further study.

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Decision Guides

Each Decision Guide is a personalized, interactive dialogue that enables you to assess symptoms, severity, and appropriate steps through a series of yes/no questions. From a child’s sore throat to headaches in teens… from tremors to tinnitus…hot flashes to hip pain, the Decision Guides cover the most common symptoms in adults and children.

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